Zodiac HST OG2
Advanced Mixed-Mode Chromatography for Strong Bases and Polar Compounds
The Zodiac HST OG2 column is a highly versatile mixed-mode analytical column, featuring weak acidic ion-pairing groups embedded in long hydrophobic ligand chains. With a pKa value of 2, it is optimized for retaining strong basic compounds and dibases, while also offering enhanced separation for polar molecules.
Why Choose Zodiac HST OG2?
The Zodiac HST OG2 column combines powerful retention mechanisms and versatile interactions, making it the ideal choice for separating strong bases, polar molecules, and acidic compounds in a wide range of analytical applications.
- Cation-Exchange Mechanism: Enhances retention of strong basic compounds by interacting with their positive charges.
- Reverse-Phase Retention: At mobile phase ph below 2 It effectively Retains neutral compounds, ensuring reproducibility and excellent selectivity.
- Ion-Exclusion Mechanism: Effectively elutes acidic compounds, offering an additional dimension of separation.
- Polar Molecule Interaction: Provides additional selectivity for separating isomers and structurally-related compounds.
- pKa Value of 2: Tailored for strong bases and dibases, providing enhanced retention and separation.
- Mobile Phase Compatibility: Suitable for LC-MS, preparative chromatography, and low UV detection applications.
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