Zodiac HST C
Advanced Retention for Amines and Metal Ions

The Zodiac HST C column is a powerful mixed-mode analytical column designed for separating strong bases, di-bases, and amine compounds. With a pH of 3.5, this column offers unique interactions, including host-guest complexation with amino compounds and metal ions, providing enhanced selectivity and retention.
Why Choose Zodiac HST C Column?
The Zodiac HST C column offers a unique combination of complexation and reverse-phase interactions, making it ideal for separating amines, metal ions, and neutral compounds with enhanced selectivity.
- Host-Guest Complexation: Through Cation-Exchange Mechanism Improves retention of positively charged compounds, especially amines such as Primary and Secondary amine groups forming weak Host-Guest Complexes,
- Selective Retention of Amines: Retention order for amines: tertiary < secondary < primary.
- Reverse-Phase Retention: Retains neutral compoundswith high reproducibility and selectivity.
- Ion Selectivity: Alkali metals retained in reverse order: K+ < Na+ < Li+(distinct from classical ion-exchange).
- Mobile Phase Compatibility: Suitable for LC-MS, preparative chromatography, and low UV detection.
- pKa Value of 3.5: Optimized for the separation of amine compoundsand metal ions.
Details Will be updated soon…!
- HPLC Determination of Desmosine on Zodiac HST C Column
- HPLC Retention of Obidoxime
- HPLC Separation of Surfynol 420
- HPLC Retention of Trimipramine on Zodiac HST C
- Separation Study of Zemuron Active Ingredient in Mixed-Mode HPLC
- HPLC Analysis of Pyridylacetic Acid Isomers on Zodiac HST C Column
- HPLC Analysis of Drugs
- Impact of Organic Modifier on Cation Complex Separation Using Zodiac HST C
- HPLC Separation of Aminobutyric Acid Isomers Using Mixed-Mode Chromatography
- Separation of Acetaminophen and 4-Aminophenol on Zodiac HST C
- HPLC Analysis of Codeine-Containing Drug Formulation: Influence of Buffer Concentration and pH on Separation
- Analysis of Codeine and Related Impurities in Drug Composition using Zodiac HST C
- HPLC Analysis of Dextromethorphan-Containing Formulation
- HPLC Analysis of Dextromethorphan Formulation: Impact of Buffer pH on Separation
- HPLC Analysis of NyQuil Active Ingredients
- HPLC Separation of Polar Drugs with MS-compatible Method
- HPLC Separation of Histamine and Phenethylamine on Zodiac HST C Column
- Effect of pH on Retention of Basic Compounds on Zodiac HST C Column
- HPLC Seperation of Alginic Acid in Heartburn Tablets
- HPLC Separation of Alginic Acid and Related Products
- Analysis of Antibiotics in Fish Production using Zodiac HST C Column
- HPLC Separation of Common Antibiotics in Fish Farming
- Seperation of Alkali cation on Zodiac HST C Column
- HPLC Analysis of Acetaminophen, Phenylephrine, and Diphenhydramine on Zodiac HST C Column
- Effect of Mobile Phase pH on Cation Exchange Separation Using the Zodiac HST C Column
- Buffer-Fess Ion Chromatography(BFIC) of Aspartame: Organic Modifier Effect
- HPLC Analysis of Acetylcholines
- HPLC Analysis of Vitamin B
- Retention control of Benzylamines using Zodiac HST C
- Separation of NyQuil Active Ingredients on Zodiac HST C
- Separation of Quaternary Amines on Zodiac HST C
- HPLC Analysis of Codeine Formulation: Influence of Buffer Concentration and pH on Separation
Ordering Information for HST columns :
Column Diameter | 2.1 mm, 3.2 mm, 4.6 mm, 10 mm, 22 mm |
Column Length | 10 mm, 25 mm, 50 mm, 100 mm, 150 mm, 250 mm, Guard |
Particle Size | 2.7 µm, 3 µm, 5 µm, 10 µm |
Pore Size | 90 Å, 100 Å |
Brand | Zodiac HST |
For example for Zodiac HST A column of particle size of 5 micron, 100Å pore-size, with Column dimension of 250mm x 4.6mm, 5um – The code : ZLS.HSTA.46.250.05.10
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