HPLC Method for Analysis of Propranolol on Zodiac HST OG2 column

Home HPLC Method for Analysis of Propranolol on Zodiac HST OG2 column

Description

Propranolol is a non-selective β-adrenergic blocker used in the treatment of hypertension, arrhythmias, angina, and post-myocardial infarction management.

🧪 Column Interaction: The Zodiac HST OG2 mixed-mode column (RP + ion-exchange) utilizes embedded acidic ionizable groups to effectively retain basic analytes like Propranolol via both hydrophobic and ionic interactions.

🔬 Detection: The method employs a UV-compatible mobile phase, enabling high sensitivity and reliable quantification.

💡 Versatility: This setup provides a robust platform for analyzing other β-blockers and structurally related basic pharmaceuticals.

Condition

Column Name : Zodiac HST OG2

Compound Name : Propranolol

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