HPLC Method for Analysis of Celebrex on Zodiac HST OG2 column

Description

Celecoxib, a COX-2 selective NSAID, is widely prescribed for the management of pain and inflammation related to arthritis, menstrual cramps, and acute musculoskeletal conditions.

🧪 Column & Retention
The Zodiac HST OG2, a mixed-mode reverse-phase column, enables selective retention of celecoxib through hydrophobic and ion-exchange interactions.

⚗️ Mobile Phase
A gradient system of water, acetonitrile (MeCN), and phosphoric acid provides effective separation and peak resolution.

🔬 Detection
Detection is performed using UV at 270 nm, ensuring accurate quantification even at low concentrations.

📈 Applications
Ideal for formulation analysis, stability studies, and routine quality control of celecoxib in pharmaceutical preparations.

Condition

1. Celebrex