Description
Creatine, a naturally occurring compound in muscles, plays a crucial role in energy production during high-intensity exercise. Synthesized from amino acids, it is stored in muscles for rapid energy release. In contrast, creatinine is a waste product generated from the breakdown of creatine, filtered by the kidneys, and excreted in urine. Measuring creatinine levels in blood and urine is a common diagnostic tool for assessing kidney function, as elevated levels may indicate kidney impairment or other health concerns.
The separation and analysis of creatine and creatinine can be effectively performed using a Zodiac HST OG2 mixed-mode stationary phase column. This process employs an isocratic method with a straightforward mobile phase comprising water, acetonitrile (MeCN), and phosphoric acid as a buffer, with UV detection for precise results.
Condition
Column Name : Zodiac HST OG2
Compound Name : Creatine, Creatinine
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