Analysis of Xylitol on Zodiac HST S1

Xylitol, a polyalcohol used as a sweetener for people with diabetes, is naturally found in fruits and vegetables. As a highly polar, non-ionizable molecule, it can be effectively retained and analyzed on the Zodiac HST S1 HILIC column. The method utilizes a mobile phase with a high water concentration to dissolve xylitol during high acetonitrile HILIC applications. The polar surface of the Zodiac HST S1 column ensures controlled retention times, making it a robust method for analyzing various sugar-like compounds.