Speciality Columns

Zodiac Specialty Columns: HST Series

The Zodiac HST Series offers state-of-the-art specialty columns engineered for diverse and challenging chromatographic applications. These columns provide unique interaction mechanisms, making them indispensable tools for advanced separations.

1. Zodiac HST HB Column: Hydrogen Bonding Specialist

• Purpose: Exclusively focuses on hydrogen-bonding interactions, ensuring effective separation for analytes heavily reliant on hydrogen bonding.
• Application: Ideal for analytes where hydrogen bonding plays a critical role in their retention and selectivity.

2. Zodiac HST P1 and HST P2 Columns: Advanced Mixed-Mode Capabilities:

The HST P1 and HST P2 columns combine reverse-phase, pi-pi, and strong cation-exchange and anion exchange interactions, respectively offering unparalleled versatility in separations.

Core Features:

• Multi-Interaction Mechanism: Leverages one, two, or all three interactions based on the properties of the analyte, ensuring broad applicability.
• Superior Isomer Resolution:
  • Excels in separating structural isomers of aromatic compounds.
  • Pi-pi interactions enhance selectivity, resolving critical compound pairs with precision.
• Tunable Selectivity: Adjusting the acetonitrile concentration in the mobile phase allows precise control over pi-pi interactions for optimized separations.

Applications:

• Separation of structurally complex and aromatic compounds.
• Versatile use across pharmaceuticals, biomolecules, and specialty chemicals.

3. Zodiac HST RP Column: Simplified Plasma Protein Analysis

• Unique Feature: Enables direct plasma protein analysis without the need for pre-sample preparation.
• Mechanism: Utilizes anion-exchange interactions for the efficient separation of plasma proteins and related biomolecules.

Applications:

• Bioanalytical studies requiring high accuracy and minimal sample handling.
• Clinical diagnostics and biomarker discovery.