Zodiac PFP Column

Zodiac PFP Column: Unique Selectivity for Enhanced Separations

The Zodiac PFP column is a high-performance chromatography solution designed for superior selectivity and retention. As a pentafluorophenyl (PFP) phase with a propyl spacer, this bonded phase delivers reversed-phase separations that stand apart from conventional C18 silica surfaces. The presence of highly electronegative fluorine atoms on the periphery of the phenyl ring ligand allows for unique aromatic selectivity, making it an excellent choice for challenging separations.

Exceptional Interaction Types for Enhanced Retention

The Zodiac PFP column exhibits multiple interaction mechanisms that contribute to its high performance, including:

• Dispersive interactions: Effective for nonpolar compounds
• Dipole-dipole interactions: Enhancing selectivity for polar analytes
• Pi-pi interactions: Ideal for aromatic compounds
• Charge-transfer interactions: Providing superior retention for halogenated species

These diverse interaction types make the Zodiac PFP column highly versatile in separating complex mixtures, especially those containing halogenated, polar, or aromatic compounds.

Unique Selectivity Beyond C18 Columns

Unlike traditional C18 columns, which rely mainly on hydrophobic interactions, the Zodiac PFP column leverages its pentafluorophenyl phase to achieve superior separation of aromatic and polar analytes. The fluorine atoms in the PFP phase contribute to electron-withdrawing effects, making this column particularly effective for compounds with halogens, ketones, amides, and hydroxyl groups.

This enhanced selectivity makes the PFP column a preferred choice in applications where C18 columns struggle to differentiate similar compounds.

Ideal Applications for the Zodiac PFP Column

The Zodiac PFP column is well-suited for a variety of analytical applications, including:

• Pharmaceutical analysis: Separating drugs with halogen or aromatic functional groups
• Environmental testing: Detecting pesticides, herbicides, and pollutants
• Food and beverage testing: Analyzing food additives and contaminants
• Forensic analysis: Identifying drugs of abuse and related substances

With its unique retention properties, the Zodiac PFP column delivers superior resolution and peak shape for complex sample matrices.

Benefits of Using the Zodiac PFP Column

1. Enhanced Selectivity: Differentiates structurally similar analytes with greater precision.
2. Extra Retention for Halogenated Species: Provides superior separation for halogen-containing compounds.
3. Multiple Interaction Mechanisms: Improves retention and peak resolution.
4. Robust and Reliable Performance: Ensures reproducibility across multiple runs.
5. Compatible with a Wide Range of Mobile Phases: Suitable for both aqueous and organic-rich conditions.

Why Choose Zodiac PFP Columns?

At Zodiac Life Sciences, we specialize in designing high-performance chromatography solutions to meet industry demands. Our Zodiac PFP column is meticulously engineered for reversed-phase separations that outperform conventional columns, offering unmatched selectivity, superior retention, and precise peak resolution.

Whether you’re analyzing pharmaceutical compounds, environmental contaminants, or complex biochemical samples, the Zodiac PFP column ensures accurate and reliable results.

Conclusion

For laboratories requiring enhanced selectivity and retention, the Zodiac PFP column is an excellent alternative to traditional C18 columns. Its pentafluorophenyl phase, combined with multiple interaction mechanisms, allows for superior separation of halogenated, polar, and aromatic compounds. Invest in the Zodiac PFP column today and experience the next level of chromatographic performance!

Technical Details   

Silica type : Spherical
Silica Purity : 99.999 %
Carbon Load : 12 %
Surface Area : 440 m2/gram
Pore Size : 190 A
PH Range : 2.0-8.0
Particle size : 3um, 3.5um, 5um and 10um