ZODIAC HST N
Zodiac HST N Column: Versatility in Polar and Charged Analyte Separation
The Zodiac HST N column is a highly advanced mixed-mode chromatographic solution designed to tackle complex separations of polar, very polar, and charged analytes. Its innovative stationary phase incorporates both positively and negatively charged groups, separated by a hydrophilic ligand chain, ensuring efficient interaction with a wide range of analytes.
Why choose Zodiac HST N column ?
The Zodiac HST N chemistry replaces most of the columns available in the HPLC market such as Reversed phase AQ type columns, Normal phase, IC, HILIC, Ion exchange columns etc It’s an ideal column for faster method development with simple mobile phase for laboratories seeking efficient, flexible, and high-performance separation of challenging analytes in pharmaceutical, biochemical, and environmental applications.
- Multiple Separation Mechanisms: Supports Normal Phase, HILIC, ion-exclusion, cation-exchange, anion-exchange, and hydrogen bonding interactions, offering unmatched versatility.
- Enhanced Selectivity: Charged groups on the ligand are spatially optimized to allow efficient interaction with zwitterions and charged analytes without interference.
- Simultaneous Analysis: Achieves simultaneous separation of charged and neutral organic or inorganic compounds, in a single run, simplifying workflows and eliminating the need for multiple techniques.
- Direct Sample Injection: Allows direct injection without extensive cleanup or dilution, unlike ion chromatography.
- Simultaneous Analysis of charged and neutral organic and inorganic compounds which is difficult on Ion- Chromatography technique is achieved within a single HPLC run on Zodiac HST – N columns
- Broad Mobile Phase Compatibility: Works with water-acetonitrile, methanol, and acidic or buffer-modified phases such as TFA, ammonium acetate, or triethylamine acetate, making it LC-MS and ELSD compatible
- Tuneable Performance: Selectivity and retention can be adjusted by modifying pH, organic content, and buffer strength.
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