Methods, application insights, and new column updates
Zodiac Prep provides high-performance preparative chromatography columns designed for efficient purification, high sample loading, and scalable separations from laboratory research to production applications.


Zodiac C18 Prep is an exceptional general-purpose preparative column, offering the highest hydrophobic selectivity in the Zodiac series. Manufactured under stringent testing procedures, it features uniform packing for optimal bed density, allowing chemists to scale up current analytical methods and isolate impurities effectively.
L1

Zodiac C8 Prep offers a less hydrophobic phase than C18, delivering lower retentivity and faster separations for neutral or moderately hydrophobic compounds. Engineered for maximum efficiency and column life, it provides a seamless transition from analytical methods to preparative-scale purifications.
L7

Zodiac Phenyl Prep is engineered with uniform and stable packing to isolate proteins, peptides, or impurities at a larger scale. Its specific pi-pi interaction chemistry makes it highly effective for separating compounds containing isomers and aromatic rings.
L11

Zodiac Silica Prep utilizes ultra-pure fully porous silica gel with an optimum bed density for maximum column efficiency. It is engineered for the large-scale isolation of strong hydrophilic compounds in normal-phase chromatography using highly nonpolar mobile phases.
L3

Zodiac CN Prep is an excellent choice for the preparative isolation of polar molecules when standard C18 or C8 phases fail. Featuring stable packing and optimum bed density, it allows for easy scale-up of current analytical methods in either normal-phase or reversed-phase modes.
L10

Zodiac Amino Prep is chemically bonded with an aminopropyl sorbent, making it a premier choice for the large-scale separation of sugars. With uniform packing for maximum column efficiency, it is ideal for scale-ups and normal-phase or anion-exchange preparative methods.
L8

Zodiac RP Amide Prep is particularly well-suited for scaling up highly water-soluble compounds due to its polar amide groups. Offering optimum bed density and maximum column life, it is an excellent choice for scaling up separations of analytes with hydrogen bond donor characteristics.
L60

Designed for scale-up operations, Zodiac Phenyl Hexyl Prep provides a unique dual-interaction mechanism. It features uniform packing for maximum column life and performance, allowing for the precise isolation of conjugated molecules and ring substituents.
L11

Zodiac PFP Prep provides unique aromatic selectivity towards halogenated and nitro compounds due to its highly electronegative fluorine atoms. Manufactured under stringent testing procedures, it enables the efficient scale-up of analytical methods requiring pi-pi, hydrogen bonding, or dipole-dipole interactions.
L43

Zodiac HILIC Prep is tailored for the scale-up separation of strongly polar analytes that are difficult to retain on standard reversed-phase columns. It features uniform and stable packing, delivering maximum column efficiency and performance for complex sample purifications.
L3

Zodiac Diol Prep is designed for normal-phase and aqueous size-exclusion preparative chromatography. With customizable solutions and optimum bed density, it allows chemists to scale up methods for purifying delicate biological samples and polar impurities with maximum efficiency.
L20

Zodiac SCX Prep is engineered for the efficient scale-up and purification of basic compounds and peptides. It features uniform and stable packing for maximum column life, making it highly effective for isolating impurities and target analytes via strong ionic interactions.
L9

Zodiac SAX Prep provides stable packing and optimum bed density for the large-scale purification of acidic compounds. It is manufactured under stringent standards to ensure high performance and column life when transitioning anion-exchange methods from analytical to preparative scales.
L14

Zodiac Biphenyl Prep offers enhanced aromatic selectivity for compounds containing rings and conjugated systems. With optimum bed density, it ensures maximum column efficiency when scaling up analytical methods for the isolation of complex pharmaceuticals and isomers.
L11

Designed for purification and scale-up applications, Zodiac Preparative Columns deliver high loading capacity, excellent packing stability, and consistent separation performance across pharmaceutical process development and production workflows.
HPLC Columns
GC Capillary Columns
Flash Columns
SPE Cartridges
Reference Standards
Contact Us
Technical Support
Product Selection
Application Assistance
Method Development
Column Care Guide
Request a Quote
Chromatography
Applications
Lab Support
Documentation
Resources
© 2019-2026 Zodiac Life Sciences | ALL RIGHTS RESERVED.