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Sertraline HCl Related Substances Analysis using Zodiac Phenyl Column
Application ID :
AP_1164
Analytes
- Impurity-B, Impurity-D, Impurity-C, Impurity-A, Impurity-F, Sertraline HCl
Conditions
Column : Zodiac Phenyl HPLC Column
Column Size : 250mm * 4.6mm, 5mu*m
Mobile Phase :
Buffer:5.8 g of Ammonium dihydrogen phosphate in 1000 mL water, adjusted to pH 4.2 with dil OPA.
Mobile phase-A:Buffer:ACN:MeOH(80:5:15)
Mobile phase-B:Buffer:ACN:MeOH(20:30:50)
Flow Rate : 1.0 mL/min.
Buffer Details : A precise HPLC method for the determination of related substances in Sertraline HCl using the Zodiac Phenyl column. This method ensures excellent separation, high sensitivity, and reproducibility, making it ideal for pharmaceutical impurity profiling and quality control.
Detector : UV 220 nm
Column Temperature : 30 °C
Injection Volume : 20 ul
Description
A precise HPLC method for the determination of related substances in Sertraline HCl using the Zodiac Phenyl column. This method ensures excellent separation, high sensitivity, and reproducibility, making it ideal for pharmaceutical impurity profiling and quality control.
