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Sepearation Of Celecoxib Related Substances-BP-API Method

Application ID : 71

Analytes

  1. 1) Impurity A
  2. 2) Celecoxib
  3. 3) Impurity B
Conditions

Column : Zodiac Phenyl

Column Size : 250mm * 4.6mm, 5mu*m

Mobile Phase :
Buffer: 2.7g/L of KH2PO4 & Adjust to pH 3.0 with H3PO4
M.P.: Acetonitrile: Methanol: Buffer (10:30:60)

Flow Rate : 1.5 ml/min

Description
The separation of Celecoxib related substances using an API method, possibly specified by the British Pharmacopoeia (BP) and associated with Tristar Formulations. “Zodiac Phenyl” might indicate a specific phase or type of chromatography column used in the method. If you need specific details on the analytical method itself, such as chromatographic conditions (mobile phase composition, gradient program, detection wavelength, etc.), you would typically refer to the British Pharmacopoeia or relevant publications from Tristar Formulations. These sources would provide precise instructions for separating Celecoxib and its related substances using the Zodiac Phenyl column or any other specified method.