Methods, application insights, and new column updates
Palbociclib SST Analysis using Zodiac C18(1) Column
Application ID :
52
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Analytes
- Polbociclib pyridine N-oxide ,Boc-Amino pyridinylpiperzine ,Des acetyl impurity ,Palbociclib ,Palbociclib piperazine N-oxide ,Palbociclib Despyridyl analog ,Palbociclib Despyridyl bromo analog ,6-Desacetyl-6-bromo-N-Boc-Polbociclib ,Palibociclib N-Boc Allyl analog
Conditions
Column : Zodiac C18(1)
Column Size : 250mmx4.6mm,5µm
Mobile Phase :
3.4 g KH2PO4 in 1000 mL water, adjusted to pH 4.0 with dil OPA
Acetonitrile:Methanol (70:30)
Flow Rate : 1.2mL / min
Description
A robust and reliable HPLC method designed for the analysis of Palbociclib SST using the Zodiac C18(1) column (250mm × 4.6mm, 5µm). This method ensures high precision, superior resolution, and consistent performance, making it well-suited for pharmaceutical quality control and impurity assessment.
