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Related substances for Finerenone Oxalate API by HPLC
Application ID :
AN-1225
Analytes
- Finerenone Oxalate
Conditions
Column : Presto 120 PS C18
Column Size : 150mm x 4.6mm,2.7µm
Mobile Phase :
Preparation of mobile phase-A : Take 1000ml of water and
add1 ml of triflouroacetic acid and sonicare for
Preparation of mobile phase-B : Mix Water: acetonitrile (50:50%
v/v) and sonicate for degas
Flow Rate : 0.5 mL/min
Detector : UV 242 nm
Elution Mode : Gradient program
Run Time : 55 min
Column Temperature : 20°C
Injection Volume : 10 µL
Description
Finerenone (often handled in its base form or specific salt configurations like
oxalate during chemical development) belongs to the drug category of
Non-Steroidal Mineralocorticoid Receptor Antagonists (MRAs).In accurate
analysis of the active pharmaceutical ingredient requires effective
separation of Finerenone from its related impurities.This HPLC application
demonstrates the separation of Finerenone using a Presto 120 PS column.
The method provides a clear chromatographic profile with Finerenone
eluting at approximately 9.708 minutes, while the observed impurities are
separated at approximately 11.332 and 24.486 minutes.
oxalate during chemical development) belongs to the drug category of
Non-Steroidal Mineralocorticoid Receptor Antagonists (MRAs).In accurate
analysis of the active pharmaceutical ingredient requires effective
separation of Finerenone from its related impurities.This HPLC application
demonstrates the separation of Finerenone using a Presto 120 PS column.
The method provides a clear chromatographic profile with Finerenone
eluting at approximately 9.708 minutes, while the observed impurities are
separated at approximately 11.332 and 24.486 minutes.
