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In-house Assay for Telmistran and Hydrochlothiazide Tablets 80/25mg by HPLC
Application ID :
AN-1215/2
Analytes
- Telmistran and Hydrochlothiazide
Conditions
Column : Presto 120 C8 AQ
Column Size : 150mm*4.6mm, 2.7µm
Flow Rate : 0.5 mL/min
Buffer Details : Dissolve 2.0g of ammonium dihydrogen orthophosphate in 1000ml of water and adjust pH with phosphaoric acid to pH 3.0.
Detector : UV 270 & 298 nm
Elution Mode : Gradient program
Run Time : 16 min
Column Temperature : 40°C
Injection Volume : 10 µL
Description
Telmisartan: Angiotensin II receptor blocker (ARB / angiotensin
receptor antagonist). It blocks a chemical in the body that narrows
blood vessels, allowing them to relax and widen.
Hydrochlorothiazide: Thiazide diuretic. It helps the kidneys remove
extra water and salt through urine, which reduces fluid volume in the
body and lowers blood pressure.This HPLC application demonstrates
the separation of Hydrochlorthiazide and Telmisartan using a Presto
C8 column. The method provides a clear chromatographic peaks with
Hydrochlorthiazide and Telmisartan eluting at approximately 4.941 and
12.190 minutes respectively.
receptor antagonist). It blocks a chemical in the body that narrows
blood vessels, allowing them to relax and widen.
Hydrochlorothiazide: Thiazide diuretic. It helps the kidneys remove
extra water and salt through urine, which reduces fluid volume in the
body and lowers blood pressure.This HPLC application demonstrates
the separation of Hydrochlorthiazide and Telmisartan using a Presto
C8 column. The method provides a clear chromatographic peaks with
Hydrochlorthiazide and Telmisartan eluting at approximately 4.941 and
12.190 minutes respectively.
