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Cefuroxime acid & 3-OH Cefuroxime acid Analysis using Zodiac C18(1) Column

Application ID : AP_1151

Analytes

  1. 3-Hydroxy Ceforoxime acid, Ceforoxime acid
Conditions

Column : Zodiac C18(1)

Column Size : 150X4.6mm;5μ

Mobile Phase :
Transfer 50 mL of 0.1 M Sodium acetate to 1000 mL volumetric flask. Dilute with 0.1 N acetic acid to volume
and mix to get 1000 mL, adjust the pH 3.4 with dilute NaOH or acetic acid
50% pH 3.4 acetate buffer & 50% Acetonitrile 50

Flow Rate : 1.5 mL/min.

Description
A robust and reliable HPLC method designed for the analysis of Cefuroxime acid & 3-OH Cefuroxime acid using the Zodiac C18(1) column (150mm × 4.6mm, 5µm). This method ensures high precision, superior resolution, and consistent performance, making it well-suited for pharmaceutical quality control and impurity assessment.