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Bortezomib- IP method on Zodiac C8(1)

Application ID : 29

Analytes

  1. Unknown Imp.1
  2. Unknown Imp.2
  3. Bortezomib
  4. Unknown Imp.3
  5. Unknown Imp.4
Conditions

Column : Zodiac C8(1) HPLC Column

Column Size : 150mmx4.6mm, 5µm

Mobile Phase :
ACN:H2O:HCOOH (35:65:0.1)

Flow Rate : 1.0 ml/min

Description
The Zodiac C8(1) column, featuring a octyl (C8) bonded silica stationary phase, is engineered for optimal separation in reversed-phase high-performance liquid chromatography (RP-HPLC). Its moderate hydrophobicity and excellent surface stability allow for precise resolution of Bortezomib, ensuring efficient separation from impurities and related substances. The column’s advanced design enhances peak shape and retention time control, making it a reliable choice for the accurate and reproducible analysis of Bortezomib in pharmaceutical applications.