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Assay Method for Atorvastatin by HPLC_IP

Application ID : AN-1232

Analytes

  1. Atorvastatin
Conditions

Column : Presto 120 C18

Column Size : 150mm x 4.6mm,2.7µm

Mobile Phase :
Buffer: 1.54g Ammonium Acetate in 1000mL water and adjust pH to 4.0 with Glacial Acetic acid.

Flow Rate : 0.5 mL/min

Description
Atorvastatin is a statin drug widely used to reduce cholesterol levels and
manage cardiovascular risk. An HPLC assay method was developed for
the determination of Atorvastatin using a Presto 120 C18 column. The
chromatographic separation produced a sharp and symmetrical
Atorvastatin peak at a retention time of approximately 9.82 minutes,
demonstrating good chromatographic performance. The method provides
a suitable approach for the routine assay of Atorvastatin in pharmaceutical
analysis.