Methods, application insights, and new column updates
Aciclovir API EP Method on Zodiac C18(1)
Application ID :
AP_1142
Analytes
- Related Compound-B, Related Compound-P, Aciclovir, Related Compound-C, Related Compound-N, Related Compound-O, Related Compound-Q, Related Compound-J, Related Compound-I, Related Compound-F, Related Compound-G, Related Compound-K
Conditions
Column : Zodiac C18(1) Column
Column Size : 250mmx4.6mm, 5µm
Mobile Phase :
Buffer: 3.48g/L K2H2PO4 in H2O adjust pH 2.5 with H3PO4 <br> Buffer: 3.48g/L K2H2PO4 in H2O adjust pH 3.1 with H3PO4 <br> M.P.A: Acetonitrile: Phosphate Buffer pH 3.1 (10:990) <br> M.P.B: Acetonitrile: Phosphate Buffer pH 2.5 (500:500)
Flow Rate : 1.0 ml/min
Description
The Zodiac C18 (1) 250mm x 4.6mm, 5µm is a reversed-phase HPLC column used for separating Aciclovir from its related compounds. It uses gradient elution with phosphate buffers and acetonitrile, UV detection at 254 nm, and a 1.0 mL/min flow rate. Ideal for pharmaceutical analysis of Aciclovir and impurities.
