We have imported template successfully. To setup it in the correct way please, save this page, refresh and select it in dropdown.

In-house Assay for Telmistran and HydrochlothiazideTablets 80/25mg by HPLC

Application ID : AN-1215

Analytes

  1. Telmistran and Hydrochlothiazide
Conditions

Column : Zodiac C8

Column Size : 125mm*4.0mm, 5.0µm

Flow Rate : 1.2 mL/min

Buffer Details : Dissolve 2.0g of ammonium dihydrogen orthophosphate in 1000ml of water and adjust pH with phosphaoric acid to pH 3.0.

Detector : UV 270 Hydrochlorthiazide & 298nm Telmisartan

Elution Mode : Gradient program

Run Time : 16 min

Column Temperature : 40°C

Injection Volume : 10 µL

Description
Telmisartan: Angiotensin II receptor blocker (ARB / angiotensin
receptor antagonist). It blocks a chemical in the body that narrows
blood vessels, allowing them to relax and widen.
Hydrochlorothiazide: Thiazide diuretic. It helps the kidneys remove
extra water and salt through urine, which reduces fluid volume in the
body and lowers blood pressure.This HPLC application demonstrates
the separation of Hydrochlorthiazide and Telmisartan using a Zodiac
C8 column. The method provides a clear chromatographic peaks with
Hydrochlorthiazide and Telmisartan eluting at approximately 3.313 and
9.749 minutes respectively.