Methods, application insights, and new column updates
Fexofinadine HCL USP Method on Zodiac Phenyl
Application ID :
63
Analytes
- Fexofenadine Hydrochloride
- Unknown Impurity
Conditions
Column : Zodiac Phenyl HPLC Column
Column Size : 250mmx4.6mm, 5µm
Mobile Phase :
Buffer: 0.77g/L Ammonium Acetate in H2O Buffer: 6.64g NaH2PO4 & 0.84g Sodium Perchlorate in 1L Adjust PH 2.0 with H3PO4 Buffer: Acetonitrile (650:350) & add 3ml of triethylamine
Flow Rate : 1.5 ml/min
Description
The Zodiac Phenyl column (250 mm × 4.6 mm, 5 µm) is a reversed-phase HPLC column featuring a phenyl-functionalized stationary phase, which is ideal for separating aromatic and moderately polar compounds. The phenyl group on the silica surface provides π-π interactions, making it particularly effective for analyzing aromatic compounds like Fexofenadine Hydrochloride and related impurities.
