Separation of Caffeine
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Core-shell mixed-mode columns offer unique selectivity which comes from the presence of two mechanisms – reversed-phase and ion-exchange. The alternative selectivity of mixed-mode columns can be used when order of elution or resolution between compounds needs improvement. Even for neutral compounds a different selectivity can be obtained. A method for common components of headache medications (acetaminophen, caffeine, and benzoate) was developed on our Coresep 100 column. Efficiency and peak shape are comparable to leading brand core-shell reversed-phase columns.
Application Name : Selectivity Difference for Polar Compounds on Core-Shell Column in Reversed-Phase and Mixed-Mode
Column Name : Coresep 100 Columns
Analytes : Acetaminophen, Caffeine, Benzoic acid
Application Name : Acidic compounds
Column Name : Zodiac C18(1) HPLC Column
Analytes : Sorbic acid, Salicylic acid, Uracil, Caffeine, Propyl paraben
Application Name : Blood Alcohols
Column Name : GRS – 1 GC Capillary Column
Analytes : Caffeine, Cocaine, Ethanol, Methanol, acetone, Methadone, acetaldehyde, Isopropanol
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